Soon after Nrf2 was identified, a flurry of scientific discoveries began to show how Nrf2 also regulated our genes involved in the production of a wide range of antioxidant enzymes. These protective pathways are involved in seemingly unrelated areas of health from immune function to cognitive function – but they all share in common the Nrf2 “switch” that enables cells to protect themselves from both internal and external environmental challenges. In effect, Nrf2 activation enables our cells to make their own antioxidants to help us survive – and thrive – in stressful situations.
How does Nrf2 work?
When activated, Nrf2 turns on the production of specific antioxidants the body needs to fight oxidative stress effectively. Certain phytochemicals (natural, plant-based ingredients) such as turmeric, ashwagandha, bacopa, green tea, and milk thistle work together to activate Nrf2 in your body to MAKE your own antioxidants. Turning on Nrf2 creates a cascading effect that results in the production of several very powerful antioxidants. These antioxidants produced by your body do a much better job at combating oxidative stress than dietary or vitamin sources individually. Several antioxidant enzymes, including superoxide dismutase (SOD), glutathione, and catalase are activated through the Nrf2 pathway. Many scientists believe that Nrf2 activation is the “future” of cellular protection and health promotion. This foundation of naturally activating Nrf2 to “solve” the problem of oxidative or cellular stress is a fundamentally different way of restoring balance in the body. Click to learn more: more info